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Change in sleepiness ESS item ‘dozing while talking’ and change composite Z score: Mediation regression analysis.

Journal: CNS Spectrums

Article Title: Daytime sleepiness associated with lurasidone and quetiapine XR: results from a randomized double-blind, placebo-controlled trial in patients with schizophrenia

doi: 10.1017/S1092852913000904

Figure Lengend Snippet: Change in sleepiness ESS item ‘dozing while talking’ and change composite Z score: Mediation regression analysis.

Article Snippet: In patients whose neurocognitive testing results were evaluable (based on prespecified criteria for the validity of the cognitive tests, n = 267), the effect of lurasidone 160 mg/d on cognitive performance (LS mean change 0.5, SE 0.24) was superior to both placebo (–0.16, SE 0.23, p = 0.038) and quetiapine XR (–0.24, SE 0.23, p = 0.018), as assessed by the CogState composite Z-score.

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